Description
SS‐31 Peptide | 99% Purity | Third Party Tested
SS‐31 Peptide for sale online at Peptides Link Labs. Premium quality SS‐31 research peptide with verified 99% purity, complete documentation, and fast shipping. Buy SS‐31 nootropic peptide from a trusted laboratory supplier.
SS‐31 Research Peptide Overview
SS‐31 (also known as MTP‐131) is a synthetic tetrapeptide developed by researcher. Also, It is studied primarily for its ability to target mitochondria directly, stabilize the inner mitochondrial membrane, and improve cellular energy production in preclinical models of aging, cardiac injury, and metabolic disease.
In addition, What sets SS‐31 apart from most peptides is how specifically it acts. Rather than broadly suppressing oxidative stress or triggering upstream signaling cascades, it travels directly to the inner mitochondrial membrane and binds to a phospholipid called cardiolipin, which is found almost exclusively in that location. That targeted interaction drives its core effects:
- Firstly, Cardiolipin stabilization: By binding cardiolipin, SS‐31 preserves the structural integrity of the mitochondrial inner membrane, maintaining the cristae architecture that the electron transport chain depends on for efficient ATP production.
- Reduced reactive oxygen species (ROS): Stabilizing the electron transport chain limits electron leak, which in turn reduces superoxide and other damaging ROS without broadly interfering with normal redox activity.
- Improved ATP synthesis: With less electron leak and better membrane organization, mitochondria in SS‐31 treated cells produce ATP more efficiently, a key finding across cardiac, skeletal muscle, and renal models.
- Lastly, Cytoprotection during ischemia: By preventing mitochondrial swelling and protecting cristae integrity during periods of low oxygen, SS‐31 has shown consistent protective effects in ischemia‐reperfusion injury models across multiple tissue types.
Integrated Research Applications of SS‐31 Peptide
SS‐31 has become a go‐to tool for researchers studying mitochondrial dysfunction because it works in so many tissue types where mitochondria are dense and critical. Key research areas include:
- Firstly, Heart research: This is where most of the SS‐31 work is concentrated. In animal models, it has reduced infarct size, improved heart function after ischemia, and even reversed age‐related stiffening of the heart muscle. It has progressed to clinical trials for Barth syndrome and heart failure with preserved ejection fraction.
- Secondly, Muscle and aging research: In older animals, SS‐31 has brought mitochondrial energy output closer to what is seen in younger subjects, with improvements in both resting muscle function and recovery. It is a useful compound for studying how energy metabolism changes with age.
- Kidney research: SS‐31 has shown strong protective effects in renal ischemia models, preserving kidney cell structure and reducing oxidative damage during and after blood flow disruption.
- Finally, Brain and neurodegenerative research: Studies have looked at SS‐31 in Parkinson’s, Alzheimer’s, and stroke models, where protecting mitochondrial function in neurons appears to reduce cell death and support recovery.
Analytical Validation, Formulation, and Storage of SS‐31 Peptide
SS‐31 is supplied as a lyophilized white powder in glass vials at ≥99% purity, verified by HPLC with a batch‐specific certificate of analysis.
Formulation: Lyophilized powder for reconstitution with an appropriate solvent like BAC water, and supplied without dosing instructions of any kind.
Storage follows standard peptide handling practice:
- Store lyophilized vials at or below −20 °C in a cool, dark, dry environment.
- After reconstitution, refrigerate at 2–8 °C, avoid repeated freeze‐thaw cycles, and use within laboratory‐defined timeframes.
NextGenPeps supplies SS-31 as a high purity research peptide intended strictly for controlled laboratory use in vitro or in established animal models, such as murine systems. Hence, This compound is not approved as a drug, diagnostic, or dietary ingredient in this context, and is not manufactured, packaged, or marketed for consumption, self experimentation, clinical application, or any use outside properly designed and ethically approved research protocols.
Chemical Properties of SS‐31 Peptide
Frequently Asked Questions of SS‐31 Peptide
Common Research Questions
What is SS-31 peptide?
SS-31, also known as Elamipretide, is a synthetic tetrapeptide designed to target mitochondria. It is cell-permeable and selectively binds to cardiolipin in the inner mitochondrial membrane. SS-31 is studied for its ability to reduce oxidative stress and improve mitochondrial function. Researchers use it in models of age-related decline and organ damage.
What does SS-31 do?
SS-31 neutralizes reactive oxygen species at the mitochondrial level, stabilizes cardiolipin, and optimizes electron transport chain efficiency in cell studies. Also, It reduces mitochondrial swelling and cytochrome c release during stress. Research shows improved ATP production and decreased inflammation in tissue injury models. SS-31 supports cellular energy metabolism without altering membrane potential. Its actions are examined in cardiac, renal, and neurological protection studies.
What are the primary signaling pathways associated with SS‐31?
SS‐31 works by binding directly to cardiolipin on the inner mitochondrial membrane, stabilizing its structure and reducing electron leak from the energy production chain. The result is lower oxidative stress and more efficient ATP output, rather than activation of traditional receptor or kinase pathways.
Why is SS‐31 widely used in mitochondrial research?
It is one of the only peptides that can selectively accumulate inside mitochondria, giving researchers a precise way to study how membrane integrity connects to cell function and disease. Thus, The fact that it produces consistent findings across heart, kidney, brain, and muscle models adds to its value as a research tool.
What is SS-31 compared to 5-Amino-1MQ?
SS-31 directly targets mitochondria to reduce oxidative damage and stabilize membranes, while 5-Amino-1MQ inhibits NNMT to boost NAD+ levels and support broader metabolic function. SS-31 focuses on acute mitochondrial protection and ROS scavenging in injury models. In conclusion, 5-Amino-1MQ emphasizes long-term energy expenditure and fat metabolism through epigenetic-like changes. Researchers use SS-31 for organ protection and 5-Amino-1MQ for obesity and longevity studies. Both address mitochondrial health through different mechanisms.
Product Questions about SS‐31 Peptide
How is SS-31 packaged?
SS-31 is supplied in the product format and quantity shown for the selected variant. Please inspect the sealed package when it arrives and contact support promptly if the package or labeling appears damaged.
How is SS-31 shipped?
Orders are shipped within the United States via USPS. Transit times are typically 3–7 business days, depending on destination and carrier conditions. Tracking information is provided when available.
How should SS-31 be stored?
Storage requirements are product-specific. Keep SS-31 in its original labeled container and follow the product documentation or manufacturer instructions supplied with the order. Contact support if the applicable storage guidance is not available.
What is the refund policy for SS-31?
Due to the nature of research materials, Peptides Link Labs orders are final and are not eligible for refunds, returns, or exchanges. Review the shipping and reship policies before ordering.
Is SS-31 intended for human use?
No. Peptides Link Labs materials are supplied strictly for laboratory research and development use and are not intended for human or animal consumption, clinical use, diagnostic use, cosmetic use, or dietary use.










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